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Ultram is a pain reliever for treating moderate to moderately severe chronic pain. Ultram is available as brand or generic (Tramadol). Below are the most frequently asked questions about Ultram (Tramadol).
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:: What is Ultram (Tramadol)?
Ultram (Tramadol Hydrochloride) is a FDA-approved pain-relief medication used for the treatment of moderate to moderately severe chronic pain. It is made by Ortho-McNeil, based in Raritan, New Jersey, USA.
Generic Ultram, Tramadol, is available from various US manufactures.
You can buy brand Ultram by going to our Ultram price comparison page where you can select your preferred online US pharmacy with the lowest Ultram prices, no prior prescription required.
Or if you prefer generic, you can buy Tramadol (generic Ultram) by going to our Tramadol price comparison page .
If this is your first time ordering Ultram online, see our beginner’s guide , where the process of obtaining a prescription online and ordering your medication is explained.
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:: Who should take Ultram (Tramadol)?
Ultram (Tramadol) should be used for patients who need effective relief of chronic pain. Ultram (Tramadol) may be a better choice than other pain relievers in those patients who are:
- At risk of stomach ulcers, because Ultram (Tramadol) has not been
associated with ulcers or stomach bleeding in medical studies.
- Taking certain medicines to control their high blood pressure, because Ultram
(Tramadol) does not interfere with them.
- At risk of kidney problems, because Ultram (Tramadol) does not affect the system
that helps keep the kidneys working properly.
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:: Who should not take Ultram (Tramadol)?
You should not take Ultram (Tramadol) if you:
- Are dependent on or using opioids (codeine, morphine, etc).
- Are allergic to Ultram (Tramadol) or any products containing opioid medicines
(codeine, morphine).
It is important to let your doctor know about any prescription or over-the-counter medications you are taking especially MAOI, SSRI antidepressants or any sedative medications, and if you have or have had other medical conditions especially head injury, brain tumor, seizure disorder, breathing problems, liver problems, kidney problems or alcohol/drug dependence. Your doctor may need to adjust your dosage.
Ultram (Tramadol) is not recommended for use in pregnant women unless the potential benefits outweigh the risks. There are no adequate and well-controlled studies in pregnant women. Ultram (Tramadol) is secreted in human milk, which can lead to the potential for serious adverse reactions in nursing infants. Women should notify their doctor if they become pregnant or intend to become pregnant while taking Ultram (Tramadol).
Only your healthcare provider can tell you for sure if you should or not take Ultram (Tramadol). Inform your healthcare provider, during either a physical or online consultation, about all the medicines you are taking, prescription or over-the-counter, and about any medical conditions you have or have had, including allergies.
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:: What are the different types of pain?
Pain can be chronic or acute.
Chronic pain is experiencing pain consistently and for an extended period of time. Chronic pain is usually caused by an underlying medical condition such as cancer, arthritis, nervous system damage and muscloskeletal disorders among others.
Acute pain is short-term pain and is usually associated with a specific event. Acute pain can include post-operative pain, pain from an accident, injury or over usage of joints and muscles including acute back, muscle, and joint pain from sprains, strains, fractures and broken bones.
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:: How does Ultram (Tramadol) work?
Although it is not known exactly how Ultram (Tramadol) works to help relieve pain, laboratory studies suggest at least two methods may explain its effects:
First, Tramadol and its metabolite (compound it is transformed into) bind directly to opioid receptors in the nervous system acting directly on the brain and spinal cord reducing the amount of pain.
Second, it influences the neurotransmitters norepinephrine and serotonin, which reduces the size of the pain signal passed from one nerve to another.
Ultram (Tramadol) is different from both NSAIDS (nonsteroidal anti-inflammatory drugs) such as ibuprofen, and other pain medications such as codeine or morphine.
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:: How well does Ultram (Tramadol) work?
Clinical studies involving over 800 patients with a variety of chronic pain conditions showed that pain relief with Ultram (Tramadol) 250mg per day in divided doses was comparable to five daily doses of acetaminophen 300mg with codeine 30mg (Tylenol with Codeine #3), five daily doses of aspirin 325mg with codeine 30mg, or two to three daily doses of acetaminophen 500mg with oxycodone 5mg (Tylox).
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:: How safe is Ultram (Tramadol)?
Ultram (Tramadol) has been used to relieve pain since 1995. Its safety and efficacy profile have been maintained by real-world experience as well as clinical trials.
Ultram (Tramadol) has been approved by the FDA to successfully and safely treat moderate to moderately severe chronic pain. However, Ultram (Tramadol) may not be for everyone. Make sure to read about Who should not take Ultram? .
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:: What does Ultram (Tramadol) look like?
Ultram is available as brand or generic.
Brand Ultram
Ultram 50mg tablets manufactured by Ortho-McNeil (based in Raritan, New Jersey, USA), are white, oblong, and
film-coated, with the imprint ULTRAM on one side, and 06 and 59 separated by the score line on the other side.
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Generic Ultram - Tramadol is made by various companies including the following:
Tramadol 50mg tablets by Mallinckrodt (based in Saint Louis, Missouri, USA), are white, oblong, with the imprint M on one side, and 7171 on the other.
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Tramadol 50mg tablets manufactured by Mutual
(based in Philadelphia, Pennsylvania, USA), are white and round, with the imprint of an M and a P joined together over 717 on one side, and nothing on the other side.
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Tramadol 50mg tablets manufactured by Teva (based in North Wales, Pennsylvania, USA), are white and oval, with the imprint 58 on one side, and 93 on the other side.
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Your pills may look different, consult your physician or pharmacist if you have any questions.
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:: How do I take Ultram (Tramadol)?
Ultram (Tramadol) comes in 50mg tablets only. Ultram (Tramadol) may be cut in half for 25mg doses. Ultram (Tramadol) may be taken with or without food. You may find it easiest to take your Ultram (Tramadol) tablets at the same times every day. Don't take more than 2 tablets in a four-hour period or more than 400mg (8 tablets) per day.
It is preferred to start Ultram (Tramadol) at a low dose and gradually increase the dose over 12-18 days as this will result in less side effects such as dizziness, nausea and vomiting.
You should take Ultram (Tramadol) as directed by your doctor. Do not take more medication than prescribed.
Usual Adult Dose - Patients not requiring immediate onset of effect
Oral dosage form (Tablets) - 25mg once daily every morning for 3 days, then 25mg twice daily for three days, then 25mg three times daily for 3 days, then 25mg four times daily for 3 days (100mg/day total). Thereafter the total daily dose can be increase by 50mg every 3 days to reach 50mg four times daily (200mg/day total). Once the patient tolerates this dosage, 50-100mg can be used as needed for pain relief every 4-6 hours to a maximum of 400mg per day.
Usual Adult Dose - Patients requiring rapid onset of effect
Oral dosage form (Tablets) – Ultram (Tramadol) 50mg to 100mg as needed for pain relief every 4-6 hours to a maximum of 400mg per day.
Your doctor may have a plan that varies from above, always follow your doctor’s recommendations.
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:: What if I miss a dose of Ultram (Tramadol)?
Ultram (Tramadol) is usually taken on an as-needed basis therefore missing a dose is not a problem. Otherwise, if you miss a dose, take it as soon as you remember, and do not take another dose for the amount of time prescribed. Do not take an extra tablet to make up for a missed dose. Do not take more tablets, or tablets more frequently, than your doctor prescribed as this may result in serious side effects.
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:: How should I store Ultram (Tramadol)?
Keep Ultram (Tramadol) and all medications out of children's reach.
Store Ultram (Tramadol) at room temperature in a tight container. Store away from moisture, heat and direct light. Do not keep medicine past the expiration date, dispose of properly.
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:: What is the difference between Ultram (Tramadol) and Ultracet?
Ultracet contains Tramadol, the active ingredient of Ultram, in combination with Acetaminophen (also known as the brand Tylenol). Both Ultram and Ultracet are manufactured by Ortho-McNeil.
Ultracet’s combination of Tramadol and non-prescription Acetaminophen provides faster pain relief than Tramadol alone and lasts longer than Acetaminophen alone, therefore providing better pain relief than either medicine used alone. Since Ultracet contains Acetaminophen, it may not be for everyone.
Since Ultracet is faster acting than Ultram (Tramadol), Ultracet is therefore recommended for people who suffer from acute pain, while Ultram (Tramadol) is more appropriate for people who suffer from chronic pain. Since Ultracet contains Acetaminophen, it may not be for everyone (patients with liver disease).
To learn more, see our Ultracet FAQ .
For prices, see our Ultracet price comparison page and select your preferred online US pharmacy with the lowest Ultracet prices, no prior prescription needed.
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:: What else can I do to help relieve my pain?
In addition to taking your pain medication, simple changes to your daily activities and environment can help keep your pain under control.
Daily Activities:
1. Always take your medication properly as prescribed by your doctor
2. Get at least 8 hours of sleep nightly
3. Start a simple exercise program*
4. Practice mental and physical relaxation therapy
5. Get body massages
6. Use hot or cold packs
7. Have a sensible diet plan*
8. Consider physical therapy
* Losing weight by eating healthy and simple exercising, especially stretching, may significantly reduce pressure on your joints and help relieve stress on your muscles.
See our extensive Weight Loss FAQ for many guidelines including:
- How many calories should I consume in order to lose weight?
- How much weight should I lose?
- What kind of activities can I do?
- How many calories can I burn doing various activities?
- Sample exercise plans
- Sample reduced calorie menus
Changes to your environment:
1. In order to avoid pain in your hands, fingers and joints, use pain friendly devices
that simplify tasks to minimize strain, such as electric can openers.
2. Have rocker light switches, easy to open door handles and faucet handles
installed throughout your home.
3. Wear clothing with zippers instead of buttons, and shoes that are easy to put on
and off, such as Velcro straps instead of shoelaces.
Be sure to ask your doctor about these and other types of non-drug pain management techniques that might be right for you. You can also ask for referrals to specific providers of these services.
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:: What are the possible side effects of Ultram (Tramadol)?
The most common side effects reported in clinical studies were constipation, nausea, dizziness, headache, sleepiness and vomiting. These side effects were usually experienced during the beginning of therapy. These side effects can be reduced by starting patients at a low dose of Ultram (Tramadol) and gradually increasing the dose.
There is a rare chance that people taking Ultram (Tramadol) may have a seizure. The chance of this happening increases if you:
- Have or have had a seizure disorder (epilepsy), head trauma or nervous system
infections.
- Take more than the recommended dose of Ultram (Tramadol) or medications
containing Tramadol such as Ultracet.
- Are abruptly discontinuing use of alcohol or sedatives.
- Take medicines such as MAOI, SSRI, TCA or other opioids.
Take Ultram (Tramadol) as directed by your doctor to reduce the chance of experiencing a seizure. If you experience a seizure while taking Ultram (Tramadol), stop taking the tablets immediately, contact your doctor, and do not restart Ultram (Tramadol).
Side effects other than those listed here may also occur. Talk to your doctor about any side effects that seem unusual or that are especially bothersome.
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:: What other precautions should I take when taking Ultram
(Tramadol)?
In addition to the above possible side effects of Ultram (Tramadol), please be aware of the following as they apply to you.
Driving and Hazardous Work:
Ultram (Tramadol) may make you dizzy or sleepy. Use caution before driving a car or engaging in hazardous work until you know how the medicine affects you.
Consumption of Alcohol:
Do not drink alcoholic beverages while taking Ultram (Tramadol). It can result in serious side effects.
Medication Interactions:
Before you start taking Ultram (Tramadol), inform your healthcare provider, during either a physical or online consultation, about all the medicines you use, and do not start taking any prescription or over-the-counter medications without asking your doctor first. Some medications can increase side effects such as drowsiness or increase the risk of seizure, and are best avoided while taking Ultram (Tramadol). See What are the possible drug interactions of Ultram (Tramadol)?
Pregnancy and Breast Feeding:
Ultram (Tramadol) is not recommended for use in pregnant women unless the potential benefits outweigh the risks. There are no adequate and well-controlled studies in pregnant women. Ultram (Tramadol) is secreted in human milk, which can lead to the potential for serious adverse reactions in nursing infants. Women should notify their doctor if they become pregnant or intend to become pregnant while taking Ultram (Tramadol).
Kidney and Liver Disease:
The side effects may be more likely due to potential for higher blood levels of Ultram (Tramadol). Depending on the severity of your condition, your doctor may need to adjust your dosage.
Adults over 65 years old:
Dosing should be more conservative as drug effects may be more pronounced due to medical conditions and other multiple drug therapy.
Do NOT share your Ultram (Tramadol) prescription with others, this can be a very dangerous practice.
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:: What are the possible drug interactions of Ultram (Tramadol)?
Inform your doctor, during either a physical or online consultation, about all the medicines you use, prescription and non-prescription. Certain medicines should never be used together. Some medicines may be used together even if an interaction might occur. In these cases, your doctor may change the dose, monitor the effects or take other precautions.
When you are taking Ultram (Tramadol), it is especially important that you inform your doctor if you are taking any of the following:
- Monoamine Oxidase (MAO) inhibitors: Furoxone (furazolidone), Nardil (phenelzine),
Eldepryl (selegiline), Marplan (isocarboxazid), Matulane (procarbazine), Parnate
(tranylcypromine)- increased risk of seizure.
- Antipsychotic medications including Haldol (haloperidol) and phenothiazines such
as Thorazine (chlorpromazine), Mellaril (thioridazine), Prolixin (fluphenazine),
Serentil (mesoridazine), Trilafon (perphenazine) - increased risk of seizure and side effects.
- Tricyclic antidepressants: Elavil (amitriptyline), Anafranil (clomipramine), Asendin
(amoxapine), Sinequan (doxepin), Aventyl/Pamelor (nortriptyline), Surmontil
(trimipramine), Asendin (amoxapine), Norpramin (desipramine), Tofranil
(imipramine), Vivactil (protriptyline)- increased risk of seizure and side effects.
- Selective serotonin reuptake inhibitor antidepressants such as: Celexa
(citalopram), Luvox (fluvoxamine), Zoloft (sertraline), Prozac (fluoxetine), Paxil
(paroxetine), Lexapro (escitalopram)- increased risk of seizure.
- Other products containing Tramadol such as Ultracet- risk of increased side
effects.
- Narcotic pain relievers such as codeine, Duragesic (fentanyl), Dilaudid
(hydromorphone), Demerol (meperidine), Vicodin/Lorcet/Lortab (hydrocodone),
MS Contin/Roxanol (morphine), Percocet/Percodan (oxycodone), Darvon/Darvocet
(propoxyphene)- increased risk of seizure and side effects.
- Phenergan (promethazine) or Compazine (prochlorperazine)- increased risk of
seizure and side effects.
- Wellbutrin/Zyban (bupropion)- increased risk of seizure.
- Tegretol (carbamazepine)- increased risk of seizure.
- Lanoxin (digoxin) and Coumadin (warfarin)- Ultram (Tramadol) affects these
medications’ potency.
- Any sedative hypnotics to help you sleep, pain reliever, muscle relaxer,
antihistamine, anxiety medication or alcohol- risk of increased side effects
especially drowsiness and reduced breathing rate.
Drugs other than those listed here may also interact with Ultram (Tramadol).
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:: Can I take Ultram (Tramadol) if I drink alcohol?
Do not drink alcoholic beverages while taking Ultram (Tramadol). It can result in serious side effects.
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:: Can I become dependent on Ultram (Tramadol)?
Opioid pain relievers such as Ultram (Tramadol) can cause dependence or a need to continue taking medication. Dependence or addiction is more common when a medication is used at high doses or for a long period of time. Although anyone can become dependent, it is more likely if you have been dependent on alcohol or other drugs in the past.
Stopping Ultram (Tramadol) abruptly may lead to an adjustment period for your body and you may experience withdrawal side effects. The length of time this takes depends on the amount of medicine you were using and how long you used it. If you have been taking Ultram (Tramadol) in large doses or for a long period of time, you should consult your doctor before stopping therapy. Your doctor may decide it is best to gradually reduce the dose to help minimize withdrawal side effects. Withdrawal symptoms may include anxiety, sweating, insomnia, rigors, pain, nausea, tremors, diarrhea, and rarely panic attacks and hallucinations.
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:: What are symptoms of a possible Ultram (Tramadol) overdose?
Symptoms of overdose may include reduced breathing rate, severe drowsiness, coma, seizure and cardiac arrest. If overdose is suspected, call your doctor, emergency medical services (EMS) 911, or the poison control center immediately.
National Poison Control Center telephone number: 800-222-1222
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:: Is Ultram (Tramadol) available over the counter?
No. Ultram (Tramadol) is currently available by prescription only.
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:: How can I get an Ultram (Tramadol) prescription online?
Go to our Ultram price comparison page where you can select your preferred online US pharmacy with the lowest Ultram prices, no prior prescription required.
Or if you prefer generic, you can buy Tramadol (generic Ultram) by going to our Tramadol price comparison page .
Our featured US-based online pharmacies work with US-licensed doctors and pharmacists to provide you with your prescriptions through an online consultation.
If this is your first time ordering Ultram online, see our beginner’s guide , where the process of obtaining a prescription online and ordering your medication is explained.
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:: How much does Ultram (Tramadol) cost?
Some companies charge less per pill but charge you separately for their consultation and pharmacy dispensing fees. Others include these fees into their final pricing.
RxPriceCheck's featured pharmacies give you a free online medical consultation with your order.
There is brand Ultram and generic Ultram (Tramadol) available. Be sure to compare Ultram prices and Tramadol prices before buying.
Usually, the more pills you buy, the cheaper the price per pill.
Generic Ultram is usually cheaper than brand especially as quantities increase. Brand or generic is really up to your preference.
Go to our Ultram price comparison page where you can select your preferred online US pharmacy with the lowest Ultram prices, no prior prescription required.
Or if you prefer generic, you can buy Tramadol (generic Ultram) by going to our Tramadol price comparison page .
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:: What is generic Ultram and is it available?
The generic name for Ultram is Tramadol . Brand Ultram and generic Tramadol are both available in 50mg tablets from various US manufacturers. See What does Ultram (Tramadol) look like? for pictures.
Generic is usually cheaper than brand. Brand or generic is really up to your preference.
Go to our Tramadol price comparison page where you can select your preferred online US pharmacy with the lowest Tramadol prices, no prior prescription required.
Compare with Ultram prices
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:: Is it safe to order Ultram (Tramadol) or other medications
from non-US pharmacies?
Purchasing Ultram or Tramadol from non-US pharmacies can be potentially dangerous. The FDA (Food and Drug Administration) does not recommend ordering medications online from pharmacies located outside the U.S. because it cannot guarantee the origin, quality or safety of the medication or regulate the manufacturers. Therefore, it may be filled with other ingredients that may harm you, or it may be fake, sold as Ultram, but not contain the active ingredient Tramadol.
RxPriceCheck.com only affiliates with online US pharmacies that work with US licensed physicians and pharmacists, and sell brand Ultram approved by the FDA and manufactured by Ortho-McNeil, or generic Ultram (Tramadol) approved by the FDA. You can therefore choose from our list of online US pharmacies with confidence.
See our Ultram price comparison page where you can select your preferred online US pharmacy with the lowest Ultram prices, no prior prescription required.
Or if you prefer generic, you can buy Tramadol (generic Ultram) by going to our Tramadol price comparison page .
If this is your first time ordering Ultram online, see our beginner’s guide , where the process of obtaining a prescription online and ordering your medication is explained.
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* The information contained in RxPriceCheck.com is for educational purposes only and is not intended as medical advice. Consult your healthcare provider regarding your medical condition. All product names are trademarks or registered trademarks of their respective holders. View our terms of use .
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