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Flexeril is a muscle relaxant for the short-term treatment of pain caused by muscle spasms. Flexeril is available as brand or generic. Below are the most frequently asked questions about Flexeril (Cyclobenzaprine).
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Flexeril tips
on Brand
or Generic
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:: What is Flexeril (Cyclobenzaprine)?
Flexeril is the brand name of Cyclobenzaprine Hydrochloride manufactured by Merck and Company based in White House Station, New Jersey, USA. Generic Flexeril, Cyclobenzaprine, is available from various US manufactures.
Flexeril (Cyclobenzaprine) is a FDA-approved prescription muscle relaxant.
You can buy brand Flexeril by going to our Flexeril price comparison page where you can select your preferred online US pharmacy with the lowest Flexeril prices, no prior prescription required.
Or if you prefer generic, you can buy Cyclobenzaprine (generic Flexeril) by going to our Cyclobenzaprine price comparison page .
If this is your first time ordering Flexeril online, see our beginner’s guide , where the process of obtaining a prescription online and ordering your medication is explained.
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:: Who should take Flexeril (Cyclobenzaprine)?
Flexeril (Cyclobenzaprine) should be used along with rest and physical therapy for the relief of muscle spasms that are caused by painful muscloskeletal conditions. Flexeril will help reduce muscle spasm and reduce the pain, tenderness and limitation of motion that can interfere with your daily functioning.
Flexeril (Cyclobenzaprine) should only be used for short periods (up to two or three weeks).
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:: Who should not take Flexeril (Cyclobenzaprine)?
You should not take Flexeril (Cyclobenzaprine) if you:
- Are currently taking or have taken a monoamine oxidase inhibitor (MAOI) within
the last 14 days.
- Have recently had a heart attack.
- Have an irregular heart beat (arrhythmias).
- Have heart block.
- Have heart conduction disturbance.
- Have congestive heart disease (CHF).
- Have over active thyroid (hyperthyroidism).
- Are allergic to Flexeril or Cyclobenzaprine.
It is important to let your doctor know about any prescription or over-the-counter medications you are taking especially MAOI, SSRI antidepressants or any sedative medications (See What are the possible drug interactions of Flexeril? ), and if you have or have had other medical conditions especially heart disease, thyroid problems, glaucoma, liver problems or kidney problems. Your doctor may need to adjust your dosage.
Flexeril (Cyclobenzaprine) should be used during pregnancy only if clearly needed. There are no adequate and well-controlled studies in pregnant women. It is not known if Flexeril (Cyclobenzaprine) is secreted in human milk, but other chemically related drugs are known to be secreted in breast milk. Women should notify their doctor if they become pregnant or intend to become pregnant while taking Flexeril (Cyclobenzaprine).
Flexeril (Cyclobenzaprine) has no effect on muscle spasm caused by brain or spinal cord disease.
Only your healthcare provider can tell you for sure if you should or not take Flexeril (Cyclobenzaprine). Inform your healthcare provider, during either a physical or online consultation, about all the medicines you are taking, prescription or over-the-counter, and about any medical conditions you have or have had, including allergies.
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:: How does Flexeril (Cyclobenzaprine) work?
Flexeril (Cyclobenzaprine) does not act directly on muscle or at the nerve-to-muscle communication point. It does primarily act on the brain stem and may also work on the spinal cord as well leading to its overall muscle relaxant activity.
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:: How well does Flexeril (Cyclobenzaprine) work?
Various clinical studies involving over 2000 patients have shown that Flexeril (Cyclobenzaprine) significantly relieves muscle spasm, reduces local pain and tenderness, increases range of motion and leads to less restriction in daily activities as compared with sugar pill.
Improvements were seen as early as the first day of therapy. Studies comparing Flexeril (Cyclobenzaprine) to Valium (diazepam) show that Flexeril (Cyclobenzaprine) is as effective or more effective in improving muscle spasm.
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:: How safe is Flexeril (Cyclobenzaprine)?
Flexeril (Cyclobenzaprine) has been used as a muscle relaxant for over 20 years. Its safety and efficacy profile have been maintained by real-world experience as well as clinical trials.
Flexeril (Cyclobenzaprine) has been approved by the FDA to successfully and safely treat muscle spasms that are associated with painful muscloskeletal conditions. However, Flexeril (Cyclobenzaprine) may not be for everyone. Make sure to read about Who should not take Flexeril? .
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:: What does Flexeril (Cyclobenzaprine) look like?
Flexeril is available as brand or generic.
Brand Flexeril
Flexeril manufactured by Merck and Company based in White House Station, New Jersey, USA, is available as 5mg, and 10mg tablets.
Flexeril 5mg tablets are 5-sided D-shaped, film coated and yellow-orange, with the imprint FLEXERIL on one side, and nothing on the other side.
Flexeril 10mg tablets are 5-sided D-shaped, film coated and butterscotch yellow, with the imprint FLEXERIL on one side and MSD 931 on the other side.
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Generic Flexeril - Cyclobenzaprine is made by various companies including the following:
Cyclobenzaprine 10mg tablets by Mylan Pharmaceuticals (based in Morgantown, West Virginia, USA), are round, film-coated and butterscotch yellow, with the imprint M on one side, and 751 on the other side.
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Cyclobenzaprine 10mg tablets manufactured by Pliva Inc (based in East Hanover, New Jersey, USA), are round, film-coated and yellow, with the imprint PLIVA on one side, and 563 on the other side.
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Cyclobenzaprine 10mg tablets manufactured by Watson Laboratories (based in Corona, California, USA), are round, film-coated and white, with the imprint DAN on one side, and 5658 on the other side.
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and others. Depending on the manufacturer, your pills may look different, consult your physician or pharmacist if you have any questions.
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:: How do I take Flexeril (Cyclobenzaprine)?
Brand Flexeril comes in 5mg and 10mg tablets while generic Flexeril (Cyclobenzaprine) comes in 10mg tablets only. Do not take more than 60mg per day. Do not use for more than 3 weeks.
You should take Flexeril (Cyclobenzaprine) as directed by your doctor. Do not take more medication than prescribed.
Usual Adult Dose
Oral dosage form (Tablets) - 10mg three times daily. The usual range is 10 to 40mg per day.
Your doctor may have a plan that varies from above, always follow your doctor’s recommendations.
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:: What if I miss a dose of Flexeril (Cyclobenzaprine)?
If you miss a dose of Flexeril (Cyclobenzaprine), take it as soon as you remember it. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do NOT double the dose to make up for a missed dose. Do not take more tablets than your doctor prescribed.
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:: How should I store Flexeril (Cyclobenzaprine)?
Keep Flexeril (Cyclobenzaprine) and all medications out of children's reach.
Store Flexeril (Cyclobenzaprine) at room temperature in a tight container. Store away from moisture, heat and direct light. Do not keep medicine past the expiration date, dispose of properly.
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:: What are the possible side effects of Flexeril (Cyclobenzaprine)?
The most common side effects are drowsiness, dry mouth, headache and dizziness. Less common are stomach pain, acid reflux, constipation, diarrhea, nausea, unpleasant taste, dizziness, tiredness, nervousness, confusion and blurred vision.
Stop taking Flexeril (Cyclobenzaprine) and contact your doctor immediately if you have signs of an allergic reaction such as a rash or hives.
Side effects other than those listed here may also occur. Talk to your doctor about any side effects that seem unusual or that are especially bothersome.
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:: What other precautions should I take when taking Flexeril
(Cyclobenzaprine)?
In addition to the above possible side effects of Flexeril (Cyclobenzaprine), please be aware of the following as they apply to you.
Driving and Hazardous Work:
Flexeril (Cyclobenzaprine) may make you dizzy or sleepy. Use caution before driving a car or engaging in hazardous work until you know how the medicine affects you.
Consumption of Alcohol:
Avoid alcoholic beverages while taking Flexeril (Cyclobenzaprine).
Medication Interactions:
Before you start taking Flexeril (Cyclobenzaprine), inform your healthcare provider, during either a physical or online consultation, about all the medicines you use, and do not start taking any prescription or over-the-counter medications without asking your doctor first. See What are the possible drug interactions of Flexeril?
Pregnancy and Breast Feeding:
Flexeril (Cyclobenzaprine) should be used during pregnancy only if clearly needed. There are no adequate and well-controlled studies in pregnant women. It is not known if Flexeril (Cyclobenzaprine) is secreted in human milk, but other chemically related drugs are known to be secreted in breast milk. Women should notify their doctor if they become pregnant or intend to become pregnant while taking Flexeril (Cyclobenzaprine).
Kidney and Liver Disease:
The side effects may be more likely due to potential for higher blood levels of Flexeril (Cyclobenzaprine). Depending on the severity of your condition, your doctor may need to adjust your dosage.
Heart Disease:
Flexeril (Cyclobenzaprine) may cause increase heart rate, irregular heartbeat, palpitations and low blood pressure. Depending on your condition your doctor may monitor you or recommend alternative therapy.
Anticholinergic Effects:
Flexeril (Cyclobenzaprine) may cause anticholinergic effects such as dry mouth, blurred vision, increase pressure in the eyes, constipation and urine retention. If you have glaucoma, trouble urinating or prostate problems your doctor may need to adjust your dose.
Patients over 65 years old:
Dosing should be more conservative as drug effects may be more pronounced due to medical conditions and other multiple drug therapy.
Do NOT share your Flexeril (Cyclobenzaprine) prescription with others, this can be a very dangerous practice.
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:: What are the possible drug interactions of Flexeril (Cyclobenzaprine)?
Inform your doctor, during either a physical or online consultation, about all the medicines you use, prescription and non-prescription. Certain medicines should never be used together. Some medicines may be used together even if an interaction might occur. In these cases, your doctor may change the dose, monitor the effects or take other precautions.
When you are taking Flexeril (Cyclobenzaprine), it is especially important that you inform your doctor if you are taking any of the following:
- Monoamine Oxidase (MAO) inhibitors: Furoxone (furazolidone), Nardil (phenelzine),
Eldepryl (selegiline), Marplan (isocarboxazid), Matulane (procarbazine), Parnate
(tranylcypromine)- there should be at least 14 days between stopping a MAO
inhibitor and starting Flexeril (Cyclobenzaprine).
- Tricyclic antidepressants: Elavil (amitriptyline), Anafranil (clomipramine), Asendin
(amoxapine), Sinequan (doxepin), Aventyl/Pamelor (nortriptyline), Surmontil
(trimipramine), Asendin (amoxapine), Norpramin (desipramine), Tofranil
(imipramine), Vivactil (protriptyline)- increased risk of side effects.
- Selective serotonin reuptake inhibitor antidepressants such as: Celexa
(citalopram), Luvox (fluvoxamine), Zoloft (sertraline), Prozac (fluoxetine), Paxil
(paroxetine), Lexapro (escitalopram)- increased risk of side effects.
- Ismelin (guanethidine): Flexeril blocks its blood pressure lowering effect.
- Ultram/Ultracet (tramadol)- Flexeril increases their seizure risk.
- Haldol (haloperidol), Wellbutrin (bupropion) - increased risk of side effects.
- Any sedative hypnotics to help you sleep, barbiturate, pain reliever, muscle
relaxer, antihistamine, anxiety medication or alcohol- risk of increased side effects
especially drowsiness and reduced breathing rate.
Drugs other than those listed here may also interact with Flexeril (Cyclobenzaprine).
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:: Can I take Flexeril (Cyclobenzaprine) if I drink alcohol?
Avoid alcoholic beverages while taking Flexeril (Cyclobenzaprine).
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:: Can I become dependent on Flexeril (Cyclobenzaprine)?
Flexeril (Cyclobenzaprine) is not addictive. Although withdrawal symptoms have not been reported with Flexeril (Cyclobenzaprine), they have been seen in other tricyclic drugs like Flexeril. When those drugs are stopped abruptly it can lead to withdrawal side effects. These withdrawal symptoms may include nausea, headache and tiredness.
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:: What are symptoms of a possible Flexeril (Cyclobenzaprine) overdose?
Symptoms of overdose may include drowsiness, increased heart rate, tremor, agitation, dizziness, slurred speech, confusion, nausea, vomiting, hallucinations, coma, seizure and cardiac arrest. If overdose is suspected, call your doctor, emergency medical services (EMS) 911, or the poison control center immediately.
National Poison Control Center telephone number: 800-222-1222
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:: Is Flexeril (Cyclobenzaprine) available over the counter?
No. Flexeril (Cyclobenzaprine) is currently available by prescription only.
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:: How can I get an Flexeril (Cyclobenzaprine) prescription online?
Go to our Flexeril price comparison page where you can select your preferred online US pharmacy with the lowest Flexeril prices, no prior prescription required.
Or if you prefer generic, you can buy Cyclobenzaprine (generic Flexeril) by going to our Cyclobenzaprine price comparison page .
Our featured US-based online pharmacies work with US-licensed doctors and pharmacists to provide you with your prescriptions through an online consultation.
If this is your first time ordering Flexeril online, see our beginner’s guide , where the process of obtaining a prescription online and ordering your medication is explained.
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:: How much does Flexeril (Cyclobenzaprine) cost?
Some companies charge less per pill but charge you separately for their consultation and pharmacy dispensing fees. Others include these fees into their final pricing.
RxPriceCheck's featured pharmacies give you a free online medical consultation with your order.
There is brand Flexeril and generic Flexeril (Cyclobenzaprine) available. Be sure to compare Flexeril prices and Cyclobenzaprine prices before buying.
Usually, the more pills you buy, the cheaper the price per pill.
Generic Flexeril is usually cheaper than brand especially as quantities increase. Brand or generic is really up to your preference.
Go to our Flexeril price comparison page where you can select your preferred online US pharmacy with the lowest Flexeril prices, no prior prescription required.
Or if you prefer generic, you can buy Cyclobenzaprine (generic Flexeril) by going to our Cyclobenzaprine price comparison page .
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:: What is generic Flexeril and is it available?
Flexeril's generic name is Cyclobenzaprine . Brand Flexeril is available in 5mg and 10mg tablets and generic Cyclobenzaprine is available in 10mg tablets from various US manufacturers. See What does Flexeril (Cyclobenzaprine) look like? for pictures.
Generic is usually cheaper than brand. Brand or generic is really up to your preference.
Go to our Cyclobenzaprine price comparison page where you can select your preferred online US pharmacy with the lowest Cyclobenzaprine prices, no prior prescription required.
Compare with Flexeril prices
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:: Is it safe to order Flexeril (Cyclobenzaprine) or other medications
from non-US pharmacies?
Purchasing Flexeril or Cyclobenzaprine from non-US pharmacies can be potentially dangerous. The FDA (Food and Drug Administration) does not recommend ordering medications online from pharmacies located outside the U.S. because it cannot guarantee the origin, quality or safety of the medication or regulate the manufacturers. Therefore, it may be filled with other ingredients that may harm you, or it may be fake, sold as Flexeril, but not contain the active ingredient Cyclobenzaprine.
RxPriceCheck.com only affiliates with online US pharmacies that work with US licensed physicians and pharmacists, and sell brand Flexeril approved by the FDA and manufactured by Merck and Company, or generic Flexeril (Cyclobenzaprine) approved by the FDA and available from various US manufacturers. You can therefore choose from our list of online US pharmacies with confidence.
See our Flexeril price comparison page where you can select your preferred online US pharmacy with the lowest Flexeril prices, no prior prescription required.
Or if you prefer generic, you can buy Cyclobenzaprine (generic Flexeril) by going to our Cyclobenzaprine price comparison page .
If this is your first time ordering Flexeril online, see our beginner’s guide , where the process of obtaining a prescription online and ordering your medication is explained.
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* The information contained in RxPriceCheck.com is for educational purposes only and is not intended as medical advice. Consult your healthcare provider regarding your medical condition. All product names are trademarks or registered trademarks of their respective holders. View our terms of use .
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