:: What is Adipex?
Adipex (also called Adipex-P), a brand name of Phentermine Hydrochloride, is a
FDA-approved weight loss oral medication used for the treatment of obesity.
It is made by Gate Pharmaceuticals, based in Sellersville, Pennsylvania, USA.
Adipex (phentermine) belongs to the class of appetite suppressants called sympathomimetics. Adipex works by decreasing your appetite. It is used for the short-term management of obesity.
* For best results, Adipex, like all other weight loss medications, should be used together with a diet, exercise, and behavior program.
For guidelines on losing weight, and tools that help you keep track of your weight-loss, calorie consumption, and exercising progress by calculating your daily calorie and fat requirements as well as how many calories you can burn doing various exercises, see our extensive Weight Loss FAQ  .
You can buy Adipex by going to our Adipex price comparison page where
you can select your preferred online US pharmacy with the lowest Adipex prices, no prior prescription required.
If this is your first time ordering Adipex online, see our beginner’s guide , where the process of obtaining a prescription online and ordering your medication is explained.
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:: Who should take Adipex?
Adipex is recommended for the short-term (few weeks) treatment of obesity in patients who:
- have a Body Mass Index (BMI) of 30 kg/m2.
- have a BMI of 27 kg/m2 together with other risk factors such as high blood
pressure, diabetes, or high cholesterol.
Go to our Weight Loss FAQ where you can use our BMI calculator to find out your Body Mass Index.
Adipex is recommended for use with a diet, exercise, and behavior program in patients who have not responded to a weight reducing diet alone. Adipex is intended for patients with major weight problems, not for those with only a few pounds to lose.
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:: What is Obesity and how is it treated?
This question requires its own frequently asked questions page. Please see our extensive Weight Loss FAQ , where you will find:
1. Detailed answers to your obesity questions such as What causes obesity? or
What are the current treatment options for obesity? .
2. Many guidelines to assist you in your weight-loss efforts, such as How to start an exercise program ,
Exercising suggestions ,
sample exercise plans .
3. Easy to use calculators to help you plan your weight-loss, such as our:
- Daily Calorie Calculator that calculates the daily calorie, fat and saturated
fat requirements that you need to maintain your current weight, as well as the
daily calorie, fat and saturated fat requirements you need to lose weight.
- Body Mass Index (BMI) calculator to determine if you are overweight based
on your body fat.
- Ideal Body Weight calculator to help you set your ideal weight-loss goals
based on your height and sex.
- Calorie Burning Calculator that calculates how many calories you burn from
doing a specific type of exercise, based on your weight and on the number of
minutes you performed the exercise.
4. Very useful printable forms to keep track of your weight loss progress.
5. Many other tips on reaching and maintaing a healthy lifestyle, including links to great Sample reduced calorie menus .
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:: How does Adipex work?
The mechanism of action of the sympathomimetic appetite suppressants such as Adipex (phentermine) in the treatment of obesity is not fully known. They are thought to stimulate the release of the neurotransmitters norepinephrine and/or dopamine from the hypothalamus thereby producing a decrease in appetite.
They may also work in other ways such as decreased gastric acid secretion (decreasing digestion) or increased energy expenditure.
Most of these medications lose their effectiveness over time, so you must also follow a good diet and exercise program and learn behavior modification techniques while taking them.
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:: How well does Adipex work?
Adipex is an effective therapy for the obese patient who needs to lose weight. Studies show that patients treated with Adipex and dietary management lose more weight than those treated with sugar pill and diet.
The amount of weight loss will increase with greater caloric restriction and increased exercise. This weight loss can significantly decrease the impact of diseases associated with being overweight.
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:: How safe is Adipex?
Adipex has been used to treat obesity for many years; its safety profile has been maintained by real-world experience as well as clinical trials.
Phentermine, the active ingredient of Adipex is the most commonly prescribed appetite suppressant, accounting for 50% of all appetite suppressants sold.
Adipex has been approved by the FDA to successfully and safely treat obesity. However, make sure to read about Who should not take Adipex? .
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:: Who should not take Adipex?
Adipex (phentermine) should not be taken if you suffer from or have suffered from any of the following conditions: agitated states, psychosis, heart disease, moderate to severe high blood pressure, glaucoma, over active thyroid, alcoholism, drug abuse or dependence, known hypersensitivity to phentermine or other sympathomimetic amines.
Do not take Adipex if you are currently taking or have taken monoamine oxidase inhibitors (MAOI) within 14 days to treat depression.
Safety of Adipex in pregnancy has not been established. If you are pregnant or nursing, talk to your doctor about the potential risks involved with taking Adipex.
Only your healthcare provider can tell you for sure if you should take Adipex or not. Inform your healthcare provider, during either a physical or online consultation, about all the medicines you are taking, prescription or over-the-counter, and about any medical conditions you have or have had, including allergies.
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:: What should I tell the doctor before taking Adipex?
Before taking Adipex or any prescription medicine, you should inform your healthcare provider, during either a physical or online consultation, of your complete medical history, including medical problems, allergies and any other medications (especially monoamine oxidase inhibitors/MAOI) that you are taking (both prescription and non-prescription), even if you stopped taking them within the past 2 weeks.
Tell your doctor if you have or have ever had heart disease, high blood pressure, arteriosclerosis (narrowing of the arteries), hyperthyroidism (overactive thyroid gland), diabetes, glaucoma, kidney disease, epilepsy or another seizure disorder, mental illness or a history of drug or alcohol abuse.
If you are pregnant, plan to become pregnant, or are breast-feeding, make sure to tell your doctor.
You may not be able to take Adipex (phentermine), or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.
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:: What does Adipex look like?
Adipex, made by Gate Pharmaceuticals, comes as oblong white 37.5mg tablets with blue specs, with the imprint ADIPEX-P on one side, and two 9's separated by the score line on the other side.
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:: How do I take Adipex?
Adipex is available in 37.5mg tablets.
Adipex should be taken on an empty stomach. Take each dose with a full glass of water. As Adipex may cause sleeplessness avoid taking a dose late in the day. If taking more than one dose a day, take the last dose approximately 4 to 6 hours prior to going to bed.
The tablet may not be chewed or crushed, but may be broken in half.
The following are common doses of Adipex. The recommended dose of Adipex may be different for different patients. If your recommended dose is different from the ones listed below, do NOT change it unless your doctor tells you to do so.
Adults under Age 60
Oral dosage form (Tablets) 37.5mg once daily 30 minutes before breakfast. Alternatively, your doctor may tell you to take 37.5mg in divided doses one-half hour before meals.
Adults Age 60 and Over
Consult your physician. A reduced Adipex dose may be necessary.
Infants and Children
Adipex is NOT recommended for children under age 16.
Take Adipex exactly as directed. Do not take more than prescribed. Do not take it more often or for a longer period than you doctor ordered. If too much Adipex is taken, it may cause unwanted effects or become habit-forming .
Most people take Adipex for 3 to 6 weeks, depending on how you respond to the medication. Inform your doctor if you think that Adipex is not working after you have taken it for a few weeks. Do NOT increase the dose.
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:: What sensible weight-loss guidelines should I follow with Adipex?
Appetite suppressants such as Adipex are not a substitute for a proper diet. Adipex will help you reach your weight loss goal, but you must use it in conjunction with a diet, exercise, and behavior program. See our extensive Weight Loss FAQ for many guidelines including:
- How many calories should I consume in order to lose weight?
- How much weight should I lose?
- What kind of activities can I do?
- How many calories can I burn doing various activities?
- Sample exercise plans
- Sample reduced calorie menus
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:: Can I take Adipex if I drink alcohol?
Alcohol can increase the unwanted side effects of dizziness and lightheadedness, therefore, it is advisable to limit or abstain from drinking alcohol while taking Adipex (or other appetite suppressants).
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:: What should I do if I forget a dose of Adipex?
If you miss a dose of Adipex, take it as soon as you remember it. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do NOT double the dose to make up for a missed dose.
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:: For how long can I continue to use Adipex?
Adipex is approved for the short-term treatment of obesity. It helps you start losing weight and gives you a chance to develop better eating, exercising, and behavioral habits to continue losing weight and prevent its return on a long-term basis. Adipex will lose its effectiveness as an appetite suppressant after a few weeks of treatment which is when your new healthy eating and exercise habits will make you ready to carry on, on your own.
Most people take the Adipex for 3 to 6 weeks, depending on how you respond to the medication. If you think that Adipex is not working after you have taken it for a few weeks, inform your doctor.
Once tolerance to the appetite suppressant effects of Adipex develops, do not increase your prescribed dose to try to increase the effect. It is time for the drug to be stopped. Continuing to take Adipex may cause unwanted effects or become habit-forming.
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:: How should I store Adipex?
Keep Adipex and all medications out of children's reach.
Store Adipex at room temperature in a tight container. Store away from moisture, heat and direct light. Do not keep medicine past the expiration date, dispose of properly.
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:: What are the different formulations of Phentermine the active
ingredient in Adipex?
Phentermine , the active ingredient of Adipex, is available as tablets and capsules.
The Phentermine 37.5mg white oblong tablet is a generic version of the Adipex 37.5mg white with blue specs oblong tablet. The only difference between the brand name Adipex (manufactured by Gate Pharmaceuticals) and the generic Phentermine (manufactured by Purepac Pharmaceuticals) is price, they both contain the same active ingredient.
The yellow Phentermine 30mg capsules and the blue/clear Phentermine 30mg capsules both contain the same active ingredient (i.e. Phentermine Hydrochloride). Both of these capsules are manufactured by Eon Labs. The blue/clear version is a generic for Fastin (Fastin is no longer manufactured) and the yellow version is simply generic Phentermine. The only differences are that the blue capsules contain small pellets and the yellow capsules contain powder, and that their prices may differ. The Phentermine 15mg capsules, which are gray/yellow, are a lower dosage form of Phentermine that are also manufactured by Eon Labs.
* Please note that none of the above capsules are a generic form of Ionamin . There is no generic equivalent for the brand Ionamin, whose active ingredient is also Phentermine, but available as a 15mg and 30mg time-released resin form.
For prices, see our Ionamin price comparison page .
To learn more about these different formulations, see our Phentermine FAQ ,
where you will also find pictures of the different Phentermine pills available .
You can also go to our Phentermine price comparison page where you can select your preferred online US pharmacy with the lowest Phentermine prices,
no prior prescription required. Compare with Adipex prices .
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:: What is Fastin?
Fastin is no longer produced and sold. Fastin was the original brand name of phentermine produced by King Pharmaceuticals for SmithKline Beecham. SK-Beecham discontinued Fastin in December 1998.
Eon Labs manufactures a generic form of Fastin that looks just like the original blue/clear Fastin brand capsules. You can see it and find out more in our Phentermine FAQ .
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:: What is Ionamin?
Ionamin is a brand name of phentermine made by CellTech Pharmaceuticals. Ionamin is available as a 15mg yellow/gray and a 30mg yellow capsule that uses a special delivery system, known as resin matrix. This matrix allows the phentermine to be released in your body over an extended period of time.
Ionamin is the only slow-release Phentermine product, therefore no other generic or brand Phentermine products can be substituted for it. See the Ionamin FAQ for more.
For prices, see our Ionamin price comparison page where you can select your preferred online US pharmacy with the lowest Ionamin prices, no prior prescription required.
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:: What is the difference between Adipex and Ionamin?
Adipex 37.5mg is a brand name version of Phentermine, and Ionamin is the brand name time-released resin form of Phentermine.
Ionamin’s time-released (or slow-release) form means that the Phentermine is released in your body over an extended period of time. The effect of a single daily dose of Ionamin is comparable to Adipex regimens.
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:: What is Xenical and can I take Adipex and Xenical at the same
time?
Xenical (orlistat) is also a weight loss medication but instead of suppressing your appetite, it works by blocking the digestion and absorption of fat to help you control your fat intake.
Xenical is a non-systemic drug, therefore there are no drug interactions between Xenical (orlistat) and centrally acting weight loss medications such as Adipex (phentermine). This would seem to make Xenical a good choice to use with existing medications to increase the weight loss effects.
Unfortunately, studies conducted so far do not indicate that Xenical has an increased effect on weight loss when combined with other drugs. The combinations of Xenical with phentermine and Xenical with Meridia have both been tested in pilot clinical trials with minimal results. Larger studies need to be conducted on these combinations before any definitive conclusions can be made.
Adipex (phentermine) is not indicated for use with other weight loss medications because the safety and efficacy has not been studied. Adipex (phentermine) with Xenical would be considered an off-label use, meaning that it hasn't been approved by the FDA.
However, the FDA has approved both drugs separately, and once the agency has approved a drug, doctors may prescribe it as desired. Often combination therapies are not studied because since each individual drug has already been approved by the FDA and is on the market, the cost of the study does not directly lead to the launching of a new drug. The lack of studies does not imply the combination is unsafe, but it also does not necessarily support its safety either. The safety of the combination is established over time as patients utilize the medications.
Therfore, your physician may determine that you may safely take Adipex (phentermine) and Xenical at the same time. Prior to this determination you must inform your doctor or healthcare professional of your complete medical history, including any other medicines you may be taking (both prescription and non-prescription).
See the Xenical FAQ for more.
For prices, see our Xenical price comparison page where you can select your preferred online US pharmacy with the lowest Xenical prices, no prior prescription required.
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:: What is Phen-Pro?
Phen-Pro is the combination of Phentermine , the active ingredient in Adipex, and a low dosage of Prozac.
Any one of the following antidepressants: Celexa (citalopram), Luvox (fluvoxamine), Zoloft (sertraline), Paxil (paroxetine) may be used instead of Prozac (fluoxetine). The use of the antidepressant in the Phen-Pro cocktail is unrelated to depression. The Phen-Pro cocktail enables Phentermine to work better and for a longer period of time.
Adipex is not indicted for use with other weight loss medications because the safety and efficacy has not been studied.
Phen-Pro is considered an off-label use, meaning that it hasn't been approved by the FDA. However, the FDA has approved both drugs separately, and once the agency has approved a drug, doctors may prescribe it as desired. Often combination therapies are not studied because since each individual drug has already been approved by the FDA and is on the market, the cost of the study does not directly lead to the launching of a new drug. The lack of studies does not imply the combination is unsafe, but it also does not necessarily support its safety either. The safety of the combination is established over time as patients utilize the medications.
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:: What is Fen-Phen or Dexfen-Phen?
Fen-Phen is the combination of Fenfluramine (or Pondimin) and Phentermine , the active ingredient in Adipex.
Dexfen-Phen is the combination of Dexfenfluramine (or Redux) and Phentermine, the active ingredient in Adipex.
Fenfluramine and Dexfenfluramine were also prescription medications used as appetite suppressants for the short-term management of obesity. Combining them with Phentermine products had a greater appetite suppressant effect than either drug alone.
The FDA never approved the Fen-Phen or Dexfen-Phen combinations, but physicians prescribed them because they seemed to have promising results.
In just a short time, Fen-Phen and Dexfen-Phen became national sensations, with millions of prescriptions in 1996. By the summer of 1997, 24 cases of heart-valve deterioration in women who had taken the Fen-Phen combination were reported to the FDA. Additional reports of heart disease from patients who had taken only Fenfluramine or Dexfenfluramine prompted the FDA to request drug manufacturers to voluntarily withdraw Fenfluramine and Dexfenfluramine in September 1997. The FDA did NOT, however, request the withdrawal of Phentermine (Adipex).
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:: Does Adipex contain the banned substance Ephedra?
No. The only active ingredient in Adipex is Phentermine Hydrochloride.
Ephedra also called Ma Huang is a different chemical substance. The FDA banned the sale of dietary supplements containing ephedrine alkaloids (ephedra) after determining that there was little evidence of ephedra's effectiveness except for short-term weight loss, while confirming that the substance raises blood pressure and otherwise stresses the circulatory system. These reactions have been conclusively linked to significant adverse health outcomes, including heart ailments and strokes.
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:: Is Adipex an Amphetamine?
No. Adipex (Phentermine) is not an Amphetamine. Phentermine, the active ingredient in Adipex, does have a similar pharmacological activity to Amphetamine. The molecular structures are related but not identical.
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:: Will a urine drug test be positive if I'm taking Adipex?
* Adipex (phentermine) may cause a positive result in urine screening tests for Amphetamines because it is chemically similar to Amphetamines.
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:: What are the possible side effects of Adipex?
Adipex, like all medications, may cause side effects. Although side effects from Adipex are not common, they can occur.
The more common side effects are dry mouth, unpleasant taste, nausea, sleeplessness, headache, dizziness, stomach upset, constipation, irritability, anxiety, nervousness, restlessness or tremor. Some of these side effects may go away during treatment as your body adjusts to the medicine.
If you experience any of the following symptoms, discontinue using Adipex and call your doctor immediately:
- Chest pain
- Decreased ability to exercise
- Fainting
- Swelling of the feet or lower legs
- Trouble breathing
Side effects other than those listed here may also occur. Talk to your doctor about any side effects that seem unusual or that are especially bothersome.
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:: What other precautions should I take when using Adipex?
In addition to the above possible side effects of Adipex, please be aware of the following as they apply to you.
Adults Age 60 and Over:
There is no specific information evaluating the use of Adipex in the older adults. The side effects may be more likely and more severe in older patients, especially when taken in combination with drugs that act on the central nervous system.
Breast Feeding:
Use of Adipex (or other appetite suppressants) while breast-feeding is NOT recommended. It may pass into breast milk, causing unwanted effects in nursing babies. Please consult your doctor for advice.
Diabetes:
Adipex may affect blood sugar levels. Monitor your blood sugar levels closely and report any concerns to you physician.
Dependency:
Please use Adipex with caution as it is chemically similar to amphetamines and may lead to psychological or physical dependency. See: What are signs of a physical or mental dependence on Adipex? .
Driving and Hazardous Work:
Adipex (or other appetite suppressants) may cause dizziness, lightheadedness, drowsiness, or a decreased alertness. Do NOT drive or engage in hazardous work until you know how the medicine affects you.
Infants and Children:
Adipex (or other appetite suppressants) are NOT recommended for use by children under age 16.
Kidney Disease:
The side effects may be more likely due to higher blood levels of Adipex.
Pregnancy:
Safety of Adipex in pregnancy has not been established. Prior to taking this medication, tell your doctor if you are pregnant or attempting to become pregnant.
Surgery, Dental Procedures, or Emergency Treatment:
Medicines that are used during surgery, dental procedures, or emergency treatments with Adipex can cause serious side effects. Prior to any surgery or treatment, inform the doctor or dentist that you are using Adipex.
Do NOT share your Adipex prescription with others, this can be a very dangerous practice.
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:: What are the possible drug interactions of Adipex?
Inform your doctor, during either a physical or online consultation, about all the medicines you use, prescription and non-prescription. Certain medicines should never be used together. Some medicines may be used together even if an interaction might occur. In these cases, your doctor may change the dose, monitor the effects or take other precautions.
When you are taking Adipex (or other appetite suppressants), it is especially important that you inform your doctor if you are taking any of the following:
- Amphetamines.
- Cocaine.
- Medications for cough and colds, decongestants, or medications for hay fever or
allergies (including nose drops or sprays).
- Ritalin (Methylphenidate).
- Selective serotonin reuptake inhibitor antidepressants like: Celexa (citalopram),
Luvox (fluvoxamine), Zoloft (sertraline), Prozac (fluoxetine), Paxil (paroxetine).
- Monoamine Oxidase (MAO) inhibitors: Furoxone (furazolidone), Nardil (phenelzine), Eldepryl (selegiline), Marplan (isocarboxazid), Matulane (procarbazine), Parnate
(tranylcypromine).
- Tricyclic antidepressants: Elavil (amitriptyline), Anafranil (clomipramine), Asendin (amoxapine), Sinequan (doxepin), Aventyl/Pamelor (nortriptyline), Surmontil
(trimipramine), Norpramin (desipramine), Tofranil (imipramine), Vivactil
(protriptyline).
- High blood-pressure medications such as clonidine, guanadrel, guanethidine, or
methyldopa, vasopressors.
- Alcohol: it may increase the unwanted effects of dizziness and lightheadedness.
Drugs other than those listed here may also interact with Adipex.
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:: What are signs of a physical or mental dependence on Adipex?
The primary signs of dependence on Adipex (or other appetite suppressants) include a strong desire or need to continue taking the medicine, and a need to increase the dose to receive the effects of the medicine.
Other symptoms may include increased/decreased appetite, disregard for consequences of negative behaviors, feelings of isolation, paranoia, feelings of well-being, hallucinations, irritability and mood swings, and sleep disorders.
If you have been taking Adipex for an extended period of time or in large doses and you think you may be mentally or physically dependent on it, inform your doctor.
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:: What should I expect after I end my Adipex treatment?
Stopping Adipex may lead to an adjustment period for your body and you may experience withdrawal side effects. The length of time this takes depends on the amount of medicine you were using and how long you used it.
If you have been taking Adipex in large doses or for a long period of time, you should consult your doctor before stopping therapy. Your doctor may decide it is best to gradually reduce the dose to help minimize withdrawal side effects.
Contact your doctor if you notice any of the following side effects after you have stopped Adipex therapy: severe irritability, excessive excitedness, trouble sleeping or nightmares, extreme weakness or tiredness, trembling, severe depression, nausea or vomiting, stomach cramps or pain, or skin disease.
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:: What are the symptoms of a possible overdose of Adipex?
The possible symptoms of an overdose of Adipex may include: dizziness, lightheadedness, fainting, restlessness, confusion, hallucinations, panic, assaultiveness, fever, tremor, over active reflexes, convulsions, irregular heartbeat, irregular blood pressure, rapid breathing, severe nausea, vomiting, or diarrhea, and abdominal cramps. A period of excitement usually followed by tiredness, weakness and depression.
If someone takes a much larger dose of Adipex than recommended, call your doctor, emergency medical services (EMS) 911, or the poison control center immediately.
National Poison Control Center telephone number: 800-222-1222
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:: Is Adipex available over the counter?
No. Adipex is currently available by prescription only.
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:: How can I get an Adipex prescription online?
Go to our Adipex price comparison page where you can select your preferred online US pharmacy with the lowest Adipex prices, no prior prescription required.
Our featured US-based online pharmacies work with US-licensed doctors and pharmacists to provide you with your prescriptions through an online consultation.
If this is your first time ordering Adipex online, see our beginner’s guide , where the process of obtaining a prescription online and ordering your medication is explained.
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:: How much does Adipex cost?
Some companies charge less per pill but charge you separately for their consultation and pharmacy dispensing fees. Others include these fees into their final pricing.
RxPriceCheck's featured pharmacies give you a free online medical consultation with your order. Be sure to compare Adipex prices before buying.
Usually, the more tablets you buy, the cheaper the price per tablet.
See our Adipex price comparison page where you can select your preferred online US pharmacy with the lowest Adipex prices, no prior prescription required.
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:: What is generic Adipex and is it available?
Generic Adipex is Phentermine . The active ingredient in the brand-name Adipex and generic Phentermine is the same (phentermine hydrochoride). They are both FDA approved and available in the US.
Generic is usually cheaper than brand. Brand or generic is really up to your preference.
To learn more, see our Phentermine FAQ .
See our Phentermine price comparison page , where you can select your preferred online US pharmacy with the lowest Phentermine prices, no prior prescription required. Compare with Adipex prices .
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:: Is it safe to order Adipex or other medications from non-US
pharmacies?
Purchasing Adipex from non-US pharmacies can be potentially dangerous. The FDA (Food and Drug Administration) does not recommend ordering medications online from pharmacies located outside the US, because it cannot guarantee the origin, quality or safety of the medication, or regulate the manufacturers. Therefore, it may be filled with other ingredients that may harm you, or it may be fake, sold as Adipex, but not contain the active ingredient.
RxPriceCheck.com only affiliates with online US pharmacies that work with US licensed physicians and pharmacists, and sell brand Adipex approved by the FDA and manufactured by Gate Pharmaceuticals, as well as Phentermine (generic Adipex) approved by the FDA. You can therefore choose from our list of online pharmacies with confidence.
See our Adipex price comparison page where you can select your preferred online US pharmacy with the lowest Adipex prices, no prior prescription required.
* For best results, Adipex, like all other weight loss medications, should be used together with a diet, exercise, and behavior program.
For guidelines on losing weight, and tools that help you keep track of your weight-loss, calorie consumption, and exercising progress by calculating your daily calorie and fat requirements as well as how many calories you can burn doing various exercises, see our extensive Weight Loss FAQ .
If this is your first time ordering Adipex online, see our beginner’s guide , where the process of obtaining a prescription online and ordering your medication is explained.
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* The information contained in RxPriceCheck.com is for educational purposes only and is not intended as medical advice. Consult your healthcare provider regarding your medical condition. All product names are trademarks or registered trademarks of their respective holders. View our terms of use .
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